The Research Insights area highlights recent advances in science and medicine as well as global laboratory research. Our readers gain tremendous benefit from research discoveries in an indirect manner.
Fracture nonunions affect many patients leading to functional and psychosocial disability Several risk factors have been described and include biological
COVID is an acute respiratory infection caused by the coronavirus SARSCoV characterized by high contagiousness and mortality of the infected population which determines its high socioeconomic significance
Methotrexate is a folic acid analog with broadspectrum antineoplastic activity which is used in the treatment of various solid tumors
Singlecell sequencing has the ability to inspect the cellular heterogeneity of tissue and cancer with unprecedented details and as such provides important insights into the cellular origin and cellspecific molecular defects
Eukaryotic RNA splicing is catalyzed by the spliceosome that removes noncoding intron segments from premRNA transcripts to produce a mature mRNA for protein translation A core component of the spliceosome is the uridylaterich small nuclear RNA
Alzheimers disease is a progressive neurodegenerative disorder defined by amyloid plaques and neurofibrillary tangles accumulation AD progresses from the hippocampus through the frontal and other brain regions
In recent years our understanding of the RNAbinding protein interactome has become significantly more informed The development of methods such as RNAinteractome capture
Lymphatic vasculature plays a crucial role in maintaining tissue fluid homeostasis facilitating lipid absorption and conducting immune surveillance The proper establishment of a functional lymphatic system is vital for embryonic
The advent of highthroughput genomic data acquisition techniques has generated immense interest in the statistical and datadriven analysis of biological and biochemical interactions One such approach is network inference
Polypharmacy the use of multiple medicines has increased as the average life expectancy and the prevalence of multimorbidity has increased Adverse events caused by the administration of many drugs